The 8-year-old Louie is doing his best to grow up and cope with a large family, a doting mother, a pesky little brother, and a by-the-book, military veteran dad. Add to that a slew of holiday family squabbles, a flood, an old Rambler and a huge goldfish, and you have the background for Life with Louie. Each episode is a portrait of humor and warmth drawn from Louie Anderson's real-life experience as a child in the Midwest.
Louie, upset with being cast as the Turkey every year, single-handedly ruins the annual Cedar Knolls Elementary Thanksgiving Pageant. The principal decides that as punishment Louie needs to give a presentation on the meaning of Thanksgiving the Monday after the Thanksgiving holiday weekend. Louie tries to figure out the meaning of the holiday while his house is flooded with guests for Thanksgiving dinner, each of whom have their own unique interpretation of the holiday.