CSI: Scena del crimine (CSI: Crime Scene Investigation) è un telefilm prodotto dal network statunitense CBS le cui vicende ruotano attorno alle indagini della squadra della polizia scientifica di Las Vegas. Le indagini vengono svolte in maniera scientifica e razionale e la ricerca delle prove, con l'ausilio di tutti i mezzi offerti dalla tecnologia, è sempre l'obiettivo principale del team di investigatori. Visto il successo del telefilm sono stati creati ben due spin-off che vanno in onda contemporaneamente, CSI: Miami e CSI:NY.
Grissom and crew are called in after high roller Tony Braun, a known drug addict, is found dead in his house by a gardener. Since drug paraphernalia is discovered near his body and it is also determined that he had recently inhaled heroin, the cause of death is at first thought to be an overdose. But further examination of the corpse reveals that Braun had been restrained at some point with duct tape, leading Grissom to believe that the victim was forced to ingest lethal amounts of heroin and, perhaps, other drugs.